This module will provide an introduction to the computational methods for analysis and simulation of biochemical networks. It will cover:

• mathematical representations of biochemical networks;
• simulation of the dynamics of biochemical models using differential equations and stochastic methods
• analysis of the structural properties of biochemical networks
• analysis of the steady state control properties of biochemical networks
• calibration of biochemical models through parameter estimation techniques;
• operation and interoperation of software for systems biology.

Bioinformatics for Systems Biology, Maths for metabolic modelling.

Category of outcome	Students will be able to:
Knowledge and understanding	use the knowledge base that is the foundation of Bioinformatics.
Intellectual skills	use computational modelling to understand a) the fundamental properties of biochemical networks, and b) the properties of specific biochemical systems
Practical skills	use systems biology software to construct and analyse biochemical network models; calibrate models using experimental data.
Transferable skills and personal qualities	communicate clearly with colleagues from various academic and cultural backgrounds; plan and manage time effectively; learn effectively for the purpose of continuing professional development.

Assessment task	Length	Weighting within unit (if relevant)
Tutorial exercises modelling and data analysis Essay	2,500 words	0.25 0.50 0.25

All distance learning course materials and related resources will be available electronically through our website on registration.

The unit is a 100% distance learning course, with the core material provided as a CBT package.The course is delivered using a virtual learning environment (VLE). The material is supplied as a Computer Based training Package (CBT) and the students are guided through their study using a series of work packages presented by the VLE.

A series of assessments associated with the course must be periodically submitted to the Course Assessor or Tutors who will respond with relevant feedback.

The VLE provides a bulletin board facility that the students are encouraged to use to communicate with one another, this board is moderated by the tutors and course assessor. Students also have weekly online tutorials. Discussion of the assessments is encouraged, but the actual exercise and project work is done individually.